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Osteosarcoma of the jaw in children and young adults HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK Huh, W. W., Holsinger, F. C., Levy, A., Palla, F. S., Anderson, P. M. 2012; 34 (7): 981-984

Abstract

Pediatric jaw osteosarcoma is uncommon, and data are scarce regarding clinical presentation, prognostic factors, and outcome.A single-institution medical record review from 1983 to 2008 for 12 patients age = 21 years was undertaken for this study.Median diagnosis age was 16.3 years (range, 6.3-21.9). Nine patients had mandible tumors. Osteoblastic subtype was most common (4 patients). Most tumors were large (ie, T2; n = 8) and high-grade (n = 8). Treatment characteristics were varied. Median follow-up was 27.1 months (range, 8-252 months). Five patients had tumor necrosis <80% after chemotherapy. No deaths were observed.Jaw osteosarcoma outcome is better compared to extremity osteosarcoma, but further study is required regarding clinical prognostic factors.

View details for DOI 10.1002/hed.21850

View details for Web of Science ID 000305513100011

View details for PubMedID 21853501