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Imaging Spectrum of CNS Coccidioidomycosis: Prevalence and Significance of Concurrent Brain and Spinal Disease AMERICAN JOURNAL OF ROENTGENOLOGY Lammering, J. C., Iv, M., Gupta, N., Pandit, R., Patel, M. R. 2013; 200 (6): 1334-1346

Abstract

The purpose of this study was to evaluate the prevalence and significance of concurrent coccidioidal brain and intraspinal disease.We conducted a retrospective imaging review of 23 patients with proven coccidioidal CNS meningitis.All patients had intracranial abnormalities, and 86% (19/22) who underwent spinal imaging had signs of intraspinal disease, including leptomeningeal enhancement (84%), arachnoiditis (63%), and cord signal abnormalities (37%); seven of 15 patients (47%) who underwent myelography had complete spinal blocks.The high prevalence of concurrent brain and intraspinal coccidioidomycosis supports a low threshold for spinal imaging.

View details for DOI 10.2214/AJR.12.9264

View details for Web of Science ID 000319447700046

View details for PubMedID 23701073