Severe lactic acidosis and multiorgan failure due to thiamine deficiency during total parenteral nutrition. BMJ case reports Ramsi, M., Mowbray, C., Hartman, G., Pageler, N. 2014; 2014

Abstract

A 16-year-old perioperative paediatric patient presented with refractory lactic acidosis and multiorgan failure due to thiamine-deficient total parenteral nutrition during a recent national multivitamin shortage. Urgent empiric administration of intravenous thiamine resulted in prompt recovery from this life-threatening condition. Despite readily available treatment, a high index of suspicion is required to prevent cardiovascular collapse and mortality.

View details for DOI 10.1136/bcr-2014-205264

View details for PubMedID 24895398