Case report: Limbic system activation by intravenous lidocaine in a patient with a complex regional pain syndrome and major depression PAIN MEDICINE Leong, M. S., Solvason, H. B. 2000; 1 (4): 358-361

Abstract

Intravenous lidocaine is used to treat various neuropathic pain states. Systemic local anesthetics have been reported to cause behavioral alteration via limbic system activation. This case report describes a dramatic behavioral change in a patient receiving intravenous lidocaine and suggests a possible use of lidocaine to discriminate somatic and affective pain characteristics.

View details for Web of Science ID 000168278700012

View details for PubMedID 15101882