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Clinicopathological features and prognosis of gastric cardia adenocarcinoma: A multi-institutional U.S. study.

Clinicopathological features and prognosis of gastric cardia adenocarcinoma: A multi-institutional U.S. study. Journal of surgical oncology Amini, N., Spolverato, G., Kim, Y., Squires, M. H., Poultsides, G. A., Fields, R., Schmidt, C., Weber, S. M., Votanopoulos, K., Maithel, S. K., Pawlik, T. M. 2015; 111 (3): 285-292

Abstract

Potential differences in presentation and outcome of patients with gastric cardia adenocarcinoma (GCA) and non-cardia adenocarcinoma may exist. The aim of the present study was to compare the clinicopathological characteristics and the prognosis of GCA versus non-cardia adenocarcinoma.Patients with gastric adenocarcinoma who underwent gastric resection between 2000-2012 were identified. Clinicopathological characteristics and outcomes were analyzed based on tumor site using a 1:2 matched-control, as well as a multivariable Cox model.Among 743 patients, 80 (10.7%) patients were diagnosed with GCA. Patients with GCA were more likely to have intestinal tumor type (GCA: 80.4% versus non-cardia: 64.2%, P?=?0.04) or advanced AJCC T stage tumors (GCA 71.8% versus non-cardia 59.2%, P?=?0.03). GCA patients more likely underwent a total gastrectomy (GCA: 85.7% vs. non-cardia: 39.8%) and had a longer length-of-stay (GCA: 10 days vs. non-cardia: 8 days) (both P?

View details for DOI 10.1002/jso.23799

View details for PubMedID 25308915