Audiologic impairment associated with bilirubin-induced neurologic damage. Seminars in fetal & neonatal medicine Olds, C., Oghalai, J. S. 2015; 20 (1): 42-46

Abstract

Hyperbilirubinemia occurs commonly in neonates and is usually mild and transient, with no long-lasting sequelae. However, bilirubin-induced neurologic damage may occur in some infants. The auditory pathway is the most sensitive part of the central nervous system to bilirubin-induced toxicity, and permanent sequelae may result from only moderately elevated total serum/plasma bilirubin levels. The damage to the auditory system occurs primarily within the brainstem and cranial nerve VIII, and manifests clinically as auditory neuropathy spectrum disorder.

View details for DOI 10.1016/j.siny.2014.12.006

View details for PubMedID 25575899