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Non-coding plasmid DNA induces IFN-gamma in vivo and suppresses autoimmune encephalomyelitis INTERNATIONAL IMMUNOLOGY Boccaccio, G. L., Mor, F., Steinman, L. 1999; 11 (2): 289-296
Abstract
Regulatory sequences used in plasmids for naked DNA vaccination can modulate cytokine production in vivo. We demonstrate here that injection of plasmid DNA can suppress the prototypic T cell-mediated autoimmune disease, experimental autoimmune encephalomyelitis, by inducing IFN-gamma.
View details for Web of Science ID 000078736100018
View details for PubMedID 10069427