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CGM-measured glucose values have a strong correlation with C-peptide, HbA(1c) and IDAAC, but do poorly in predicting C-peptide levels in the two years following onset of diabetes DIABETOLOGIA Buckingham, B., Cheng, P., Beck, R. W., Kollman, C., Ruedy, K. J., Weinzimer, S. A., Slover, R., Bremer, A. A., Fuqua, J., Tamborlane, W. 2015; 58 (6): 1167-1174

Abstract

The aim of this work was to assess the association between continuous glucose monitoring (CGM) data, HbA1c, insulin-dose-adjusted HbA1c (IDAA1c) and C-peptide responses during the first 2 years following diagnosis of type 1 diabetes.A secondary analysis was conducted of data collected from a randomised trial assessing the effect of intensive management initiated within 1 week of diagnosis of type 1 diabetes, in which mixed-meal tolerance tests were performed at baseline and at eight additional time points through 24 months. CGM data were collected at each visit.Among 67 study participants (mean age [± SD] 13.3?±?5.7 years), HbA1c was inversely correlated with C-peptide at each time point (p?

View details for DOI 10.1007/s00125-015-3559-y

View details for Web of Science ID 000353893000005

View details for PubMedID 25773405

View details for PubMedCentralID PMC4416994