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SPONTANEOUS HYPOGLYCEMIC SEIZURES IN PREGNANCY - A MANIFESTATION OF PANHYPOPITUITARISM ARCHIVES OF INTERNAL MEDICINE NOTTERMAN, R. B., Jovanovic, L., Peterson, R., Solomon, G., Druzin, M., Peterson, C. M. 1984; 144 (1): 189-191

Abstract

A 32-year-old woman had seizures and coma due to severe hypoglycemia (26 mg/dL) in the 32nd week of an otherwise uncomplicated pregnancy. She responded dramatically to the administration of cortisol. Initial endocrine evaluation disclosed prolactin (PRL), corticotropin, and thyrotropin (TSH) deficiencies. The patient recovered completely with cortisol and thyroid hormone therapy and was delivered of a healthy male child at term. Endocrine reevaluations one week and six months postpartum disclosed luteinizing hormone, follicle-stimulating hormone, growth hormone, PRL, corticotropin, and probable TSH deficiencies. The cause of this panhypopituitarism has not been determined. This case suggests that the appropriate initial treatment for spontaneous symptomatic hypoglycemia in pregnancy, while awaiting further endocrine evaluation, is the administration of cortisol.

View details for Web of Science ID A1984RY30500035

View details for PubMedID 6691758