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CHARACTERIZATION OF THE EPSTEIN-BARR VIRUS ISOLATED FROM A CELL-LINE DERIVED FROM A PATIENT WITH AMERICAN BURKITTS-LYMPHOMA CANCER RESEARCH Pizzo, P. A., Magrath, I. T., Jay, G. 1981; 41 (8): 3161-3164

Abstract

Epstein-Barr viral (EBV) DNA is nearly always detectable in African Burkitt's lymphoma (BL) but is infrequently found in the histologically indistinguishable American BL. We have derived a tumor cell line from a patient with American BL which produces EBV, and we have compared this virus isolate [JLP(c)] with African BL EBV. The American JLP(c) virus immortalizes human umbilical cord lymphocytes in vitro, and its DNA is indistinguishable from African BL EBV DNA by nucleic acid hybridization and preliminary restriction endonuclease cleavage analysis.

View details for Web of Science ID A1981LZ53100032

View details for PubMedID 6265076