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Growth hormone deficiency in adults: Characteristics and response to growth hormone replacement JOURNAL OF PEDIATRICS Lieberman, S. A., Hoffman, A. R. 1996; 128 (5): S58-S60

Abstract

Despite adequate adrenal, gonadal, and thyroid hormone replacement, many adults with hypopituitarism have a recognizable syndrome of weakness and diminished sense of well-being, accompanied by alterations in metabolism and body composition, as well as increased mortality. Short-term treatment with human growth hormone improves many of these abnormalities, but a clear improvement in functional status has yet to be demonstrated. Until such an effect is shown, the use of growth hormone replacement in adults with hypopituitarism remains investigational.

View details for Web of Science ID A1996UK86800013

View details for PubMedID 8627472