Increased Speed and Image Quality in Single-Shot Fast Spin Echo Imaging Via Variable Refocusing Flip Angles JOURNAL OF MAGNETIC RESONANCE IMAGING Loening, A. M., Saranathan, M., Ruangwattanapaisarn, N., Litwiller, D. V., Shimakawa, A., Vasanawala, S. S. 2015; 42 (6): 1747-1758


To develop and validate clinically a single-shot fast spin echo (SSFSE) sequence utilizing variable flip angle refocusing pulses to shorten acquisition times via reductions in specific absorption rate (SAR) and improve image quality.A variable refocusing flip angle SSFSE sequence (vrfSSFSE) was designed and implemented, with simulations and volunteer scans performed to determine suitable flip angle modulation parameters. With Institutional Review Board (IRB) approval/informed consent, patients referred for 3T abdominal magnetic resonance imaging (MRI) were scanned with conventional SSFSE and either half-Fourier (n?=?25) or full-Fourier vrfSSFSE (n?=?50). Two blinded radiologists semiquantitatively scored images on a scale from -2 to 2 for contrast, noise, sharpness, artifacts, cardiac motion-related signal loss, and the ability to evaluate the pancreas and kidneys.vrfSSFSE demonstrated significantly increased speed (~2-fold, P?

View details for DOI 10.1002/jmri.24941

View details for Web of Science ID 000368258100032