Clinical translation of a high-performance neural prosthesis. Nature medicine Gilja, V., Pandarinath, C., Blabe, C. H., Nuyujukian, P., Simeral, J. D., Sarma, A. A., Sorice, B. L., Perge, J. A., Jarosiewicz, B., Hochberg, L. R., Shenoy, K. V., Henderson, J. M. 2015; 21 (10): 1142-1145


Neural prostheses have the potential to improve the quality of life of individuals with paralysis by directly mapping neural activity to limb- and computer-control signals. We translated a neural prosthetic system previously developed in animal model studies for use by two individuals with amyotrophic lateral sclerosis who had intracortical microelectrode arrays placed in motor cortex. Measured more than 1 year after implant, the neural cursor-control system showed the highest published performance achieved by a person to date, more than double that of previous pilot clinical trial participants.

View details for DOI 10.1038/nm.3953

View details for PubMedID 26413781