Notice: Users may be experiencing issues with displaying some pages on stanfordhealthcare.org. We are working closely with our technical teams to resolve the issue as quickly as possible. Thank you for your patience.
 

Learn about the flu shot, COVID-19 vaccine, and our masking policy »

Stanford Health Care

Cancer-Associated Venous Thromboembolic Disease, Version 1.2015 Featured Updates to the NCCN Guidelines JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK Streiff, M. B., Holmstrom, B., Ashrani, A., Bockenstedt, P. L., Chesney, C., Eby, C., Fanikos, J., Fenninger, R. B., Fogerty, A. E., Gao, S., Goldhaber, S. Z., Hendrie, P., Kuderer, N., Lee, A., Lee, J. T., Lovrincevic, M., Millenson, M. M., Neff, A. T., Ortel, T. L., Paschal, R., Shattil, S., Siddiqi, T., Smock, K. J., Soff, G., Wang, T., Yee, G. C., Zakarija, A., McMillian, N., Engh, A. M. 2015; 13 (9): 1079-1096

Abstract

The NCCN Guidelines for Cancer-Associated Venous Thromboembolic Disease outline strategies for treatment and prevention of venous thromboembolism (VTE) in adult patients with a diagnosis of cancer or for whom cancer is clinically suspected. VTE is a common complication in patients with cancer, which places them at greater risk for morbidity and mortality. Therefore, risk-appropriate prophylaxis is an essential component for the optimal care of inpatients and outpatients with cancer. Critical to meeting this goal is ensuring that patients get the most effective medication in the correct dose. Body weight has a significant impact on blood volume and drug clearance. Because obesity is a common health problem in industrialized societies, cancer care providers are increasingly likely to treat obese patients in their practice. Obesity is a risk factor common to VTE and many cancers, and may also impact the anticoagulant dose needed for safe and effective prophylaxis. These NCCN Guidelines Insights summarize the data supporting new dosing recommendations for VTE prophylaxis in obese patients with cancer.

View details for Web of Science ID 000361419800007