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Responsive Direct Brain Stimulation for Epilepsy. Neurosurgery clinics of North America Morrell, M. J., Halpern, C. 2016; 27 (1): 111-121

Abstract

Closed-loop, responsive focal brain stimulation provides a new treatment option for patients with refractory partial onset seizures who are not good candidates for potentially curative epilepsy surgery. The first responsive brain neurostimulator (RNS® System, NeuroPace), provides stimulation directly to the seizure focus when abnormal electrocorticographic is detected. Seizure reductions of 44% at one year increase to 60 to 66% at years 3 to 6 of treatment. There is no negative impact on cognition and mood. Risks are similar to other implanted medical devices and therapeutic stimulation is not perceived.

View details for DOI 10.1016/j.nec.2015.08.012

View details for PubMedID 26615113