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PLATELET MONOAMINE-OXIDASE ACTIVITY IN SUBGROUPS OF SCHIZOPHRENIC DISORDERS SCHIZOPHRENIA BULLETIN Schildkraut, J. J., Orsulak, P. J., Schatzberg, A. F., HERZOG, J. M. 1980; 6 (2): 220-225

Abstract

This article summarizes findings from a series of studies that examined platelet monoamine oxidase (MAO) activity in patients with nonaffective schizophrenic disorders and schizophrenia-related depressions. The findings indicate that mean platelet MAO activity was not different from control values in the subgroup of nonaffective schizophrenic disorders without auditory hallucinations (that is, the S-1 subgroup). However, mean platelet MAO activity was reduced in the subgroup of nonaffective schizophrenic disorders characterized by the presence of auditory hallucinations often occurring in conjunction with paranoid features (that is, the S-2 subgroup). Moreover, we found that mean platelet MAO activity was increased in schizophrenia-related depressions characterized by histories of chronic asocial, eccentric, or bizarre behavior.

View details for Web of Science ID A1980JS03200004

View details for PubMedID 7375853