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Broadening Horizons: New Antibodies Against Influenza. Cell Jackson, K. J., Boyd, S. D. 2016; 166 (3): 532-533

Abstract

Seasonal influenza vaccine formulation efforts struggle to keep up with viral antigenic variation. Two studies now report engineered or naturally occurring human antibodies targeting the influenza hemagglutinin (HA) stem, with exceptional neutralizing breadth (Joyce et al., 2016; Kallewaard et al., 2016). Antibodies with similar structural features are elicited in multiple subjects, suggesting that modified vaccine regimens could provide broad protection.

View details for DOI 10.1016/j.cell.2016.07.023

View details for PubMedID 27471961