Notice: Users may be experiencing issues with displaying some pages on stanfordhealthcare.org. We are working closely with our technical teams to resolve the issue as quickly as possible. Thank you for your patience.
 

Learn about the flu shot, COVID-19 vaccine, and our masking policy »

Stanford Health Care

Cell Transplantation on Diastolic Parameters in Patients with Nonischemic Dilated Cardiomyopathy. Stem cells translational medicine Bervar, M., Kozelj, M., Poglajen, G., Sever, M., Zemljic, G., Frljak, S., Cukjati, M., Cernelc, P., Haddad, F., Vrtovec, B. 2017; 6 (6): 1515-1521

Abstract

We sought to evaluate the physiological background and the effects of CD34(+) cell transplantation on diastolic parameters in nonischemic dilated cardiomyopathy patients (DCM). We enrolled 38 DCM patients with NYHA class III and LVEF < 40% who underwent transendocardial CD34(+) cell transplantation. Peripheral blood CD34(+) cells were mobilized by G-CSF, collected via apheresis, and injected transendocardially in the areas of myocardial hibernation. Patients were followed for 1 year. At baseline, estimated filling pressures were significantly elevated (E/e'?=?15) in 18 patients (Group A), and moderately elevated (E/e?'

View details for DOI 10.1002/sctm.16-0331

View details for PubMedID 28296283