Clinical Impact of the 2016 Update to the WHO Lymphoma Classification. Current treatment options in oncology Lynch, R. C., Gratzinger, D. n., Advani, R. H. 2017; 18 (7): 45


The 2016 revision of the WHO classification of lymphoid neoplasms includes new entities along with a clearer definition of provisional and definitive subtypes based on better understanding of the molecular drivers of lymphomas. These changes impact current treatment paradigms and provide a framework for future clinical trials. Additionally, this update recognizes several premalignant or predominantly indolent entities and underscores the importance of avoiding unnecessarily aggressive treatment in the latter subsets.

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