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Dopamine gates sensory representations in cortex JOURNAL OF NEUROPHYSIOLOGY Eshel, N., Tian, J. 2014; 111 (11): 2161-2163

Abstract

The prefrontal cortex (PFC) maintains information about relevant sensory stimuli, in a process thought to rely on dopamine release. In a recent paper, Jacob et al. (J Neurosci 33: 13724-13734, 2013) demonstrated one way in which dopamine might facilitate this process. The authors recorded from PFC neurons in monkeys during local application of dopamine. They found that dopamine increases the gain of sensory-evoked responses in putative pyramidal neurons in PFC, potentially by inhibiting local interneurons.

View details for DOI 10.1152/jn.00795.2013

View details for Web of Science ID 000339171000001

View details for PubMedID 24401705

View details for PubMedCentralID PMC4097866