Combining hiPSCs and Human Genetics: Major Applications in Drug Development. Cell stem cell Zhang, J., Li, H., Trounson, A., Wu, J. C., Nioi, P. 2017; 21 (2): 161–65

Abstract

Merging iPSC models and human genetic research has opened up new avenues in understanding disease mechanisms and target biology, which facilitate exciting translation of this research to many areas of drug development. We highlight recent applications of these combined disciplines and discuss remaining challenges and potential solutions.

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