Sticking It to the Niche: CD98 Mediates Critical Adhesive Signals in AML CANCER CELL Reinisch, A., Majeti, R. 2016; 30 (5): 662–64


In this issue of Cancer Cell, Bajaj and colleagues report that CD98, a heterodimeric protein highly expressed in acute myeloid leukemia (AML) and largely dispensable for basal hematopoiesis, plays an important role in facilitating leukemia stem cell adhesion to bone marrow vasculature and is a potential therapeutic target in AML.

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