Tetraspanin CD81, a modulator of immune suppression in cancer and metastasis ONCOIMMUNOLOGY Vences-Catalan, F., Rajapaksa, R., Srivastava, M. K., Marabelle, A., Kuo, C., Levy, R., Levy, S. 2016; 5 (5): e1120399


Cancer cells can escape the antitumor immune response by recruiting immune suppressor cells. However, although innate myeloid-derived suppressor cells (MDSCs) and T regulatory (Treg) cells accumulate normally in tumor-bearing CD81-deficient mice, both populations are impaired in their ability to suppress the antitumor immune response.

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