Skip to main content
 
Notice: Users may be experiencing issues with displaying some pages on stanfordhealthcare.org. We are working closely with our technical teams to resolve the issue as quickly as possible. Thank you for your patience.
Stanford Health Care

Characteristics and clinical outcomes of pleomorphic lobular carcinoma in situ of the breast

Characteristics and clinical outcomes of pleomorphic lobular carcinoma in situ of the breast BREAST JOURNAL Fasola, C. E., Chen, J., Jensen, K. C., Allison, K. H., Horst, K. C. 2018; 24 (1): 66–69

Abstract

Pleomorphic lobular carcinoma in situ (PLCIS) of the breast is a rare variant of lobular carcinoma in situ (LCIS). We reviewed 78 cases of PLCIS diagnosed at our institution from 1998 to 2012. Among all cases, 47 (60%) were associated with invasive carcinoma and/or ductal carcinoma in situ (DCIS) after final surgical excision. Of the 20 cases with PLCIS alone on core needle biopsy (CNB), 6 (30%) were upgraded to invasive carcinoma or DCIS after final surgical excision. Our findings support a recommendation for complete surgical excision of PLCIS when diagnosed on CNB.

View details for PubMedID 28929550