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Identifying cytokine predictors of cognitive functioning in breast cancer survivors up to 10 years post chemotherapy using machine learning JOURNAL OF NEUROIMMUNOLOGY Henneghan, A. M., Palesh, O., Harrison, M., Kesler, S. R. 2018; 320: 38–47

Abstract

The purpose of this study is to explore 13 cytokine predictors of chemotherapy-related cognitive impairment (CRCI) in breast cancer survivors (BCS) 6?months to 10?years after chemotherapy completion using a multivariate, non-parametric approach.Cross sectional data collection included completion of a survey, cognitive testing, and non-fasting blood from 66 participants. Data were analyzed using random forest regression to identify the most significant predictors for each of the cognitive test scores.A different cytokine profile predicted each cognitive test. Adjusted R2 for each model ranged from 0.71-0.77 (p's?

View details for PubMedID 29759139