Notice: Users may be experiencing issues with displaying some pages on stanfordhealthcare.org. We are working closely with our technical teams to resolve the issue as quickly as possible. Thank you for your patience.
 

Learn about the flu shot, COVID-19 vaccine, and our masking policy »

Stanford Health Care

Non-alcoholic Fatty Liver Disease: A Review of Anti-diabetic Pharmacologic Therapies JOURNAL OF CLINICAL AND TRANSLATIONAL HEPATOLOGY Snyder, H. S., Sakaan, S. A., March, K. L., Siddique, O., Cholankeril, R., Cummings, C. D., Gadiparthi, C., Satapathy, S. K., Ahmed, A., Cholankeril, G. 2018; 6 (2): 168–74

Abstract

Non-alcoholic fatty liver disease (NAFLD), the most common cause of liver disease, affects approximately 75 to 100 million Americans. Patients with concurrent NAFLD and type 2 diabetes mellitus have a higher risk of progressing to advanced fibrosis and non-alcoholic steatohepatitis compared to non-diabetics. Lifestyle modifications, including weight loss, remain the mainstay of treatment for NAFLD, as there are no medications currently indicated for this disease state. Anti-diabetic pharmacologic therapies aimed at improving insulin sensitivity and decreasing insulin production have been studied to determine their potential role in slowing the progression of NAFLD. In this review, we focus on the evidence surrounding anti-diabetic medications and their ability to improve disease progression in patients with NAFLD.

View details for PubMedID 29951362

View details for PubMedCentralID PMC6018310