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Validity of International Classification of Diseases, Ninth Revision, Clinical Modification codes for acute renal failure
Validity of International Classification of Diseases, Ninth Revision, Clinical Modification codes for acute renal failure JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY Waikar, S. S., Wald, R., Chertow, G. M., Curhan, G. C., Winkelmayer, W. C., Liangos, O., Sosa, M., Jaber, B. L. 2006; 17 (6): 1688-1694Abstract
Administrative and claims databases may be useful for the study of acute renal failure (ARF) and ARF that requires dialysis (ARF-D), but the validity of the corresponding diagnosis and procedure codes is unknown. The performance characteristics of International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes for ARF were assessed against serum creatinine-based definitions of ARF in 97,705 adult discharges from three Boston hospitals in 2004. For ARF-D, ICD-9-CM codes were compared with review of medical records in 150 patients with ARF-D and 150 control patients. As compared with a diagnostic standard of a 100% change in serum creatinine, ICD-9-CM codes for ARF had a sensitivity of 35.4%, specificity of 97.7%, positive predictive value of 47.9%, and negative predictive value of 96.1%. As compared with review of medical records, ICD-9-CM codes for ARF-D had positive predictive value of 94.0% and negative predictive value of 90.0%. It is concluded that administrative databases may be a powerful tool for the study of ARF, although the low sensitivity of ARF codes is an important caveat. The excellent performance characteristics of ICD-9-CM codes for ARF-D suggest that administrative data sets may be particularly well suited for research endeavors that involve patients with ARF-D.
View details for DOI 10.1681/ASN.2006010073
View details for Web of Science ID 000237891100020
View details for PubMedID 16641149