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Clinical predictors for prolonged intensive care unit stay in adults undergoing thoracic aortic surgery requiring deep hypothermic circulatory arrest. Journal of cardiothoracic and vascular anesthesia Augoustides, J. G., Pochettino, A., Ochroch, E. A., Cowie, D., McGarvey, M. L., Weiner, J., Gambone, A. J., Pinchasik, D., Cheung, A. T., Bavaria, J. E. 2006; 20 (1): 8-13

Abstract

The purpose of this study was to describe clinical predictors for prolonged length of stay in the intensive care unit (PLOS-ICU) after adult thoracic aortic surgery requiring standardized deep hypothermic circulatory arrest (DHCA); and to determine the incidence of PLOS-ICU after DHCA, univariate predictors for PLOS-ICU, and multivariate predictors for PLOS-ICU.A retrospective and observational study. PLOS-ICU was defined as longer than 5 days in the ICU.Cardiothoracic operating rooms and the ICU.All adults requiring thoracic aortic repair with DHCA INTERVENTIONS: None.The cohort size was 144. The incidence of PLOS-ICU was 27.8%. The mortality rate was 11.1%. Univariate predictors for PLOS-ICU were age, stroke, DHCA duration, vasopressor dependence >72 hours, mediastinal re-exploration for bleeding, and renal dysfunction. Multivariate predictors for PLOS-ICU were stroke, vasopressor dependence >72 hours, and renal dysfunction.PLOS-ICU after DHCA is common. The identified multivariate predictors merit further hypothesis-driven research to enhance perioperative protection of the brain, kidney, and cardiovascular system.

View details for DOI 10.1053/j.jvca.2005.07.031

View details for PubMedID 16458206