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HTLV-I-ASSOCIATED MYELOPATHY IN A CALIFORNIAN - DIAGNOSIS BY REACTIVITY TO A VIRAL RECOMBINANT ANTIGEN NEUROLOGY Honig, L. S., LIPKA, J. J., Young, K. Y., Weiss, J. H., Foung, S. K. 1991; 41 (3): 448-450

Abstract

A male patient developed leg numbness and weakness, and bowel, bladder, and erectile dysfunction. Examination revealed an isolated thoracic myelopathy, with lower-extremity spasticity, decreased vibration and position sense, hyperreflexia, and Babinski's signs. Serum and CSF showed antibody reactivity to human T-cell lymphotropic virus type I or II (HTLV-I/II), suggesting HTLV-I-associated myelopathy. Antibody reactivity to a unique HTLV-I recombinant protein provided definitive diagnosis of HTLV-I infection.

View details for Web of Science ID A1991FD56600028

View details for PubMedID 1706492