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SIGNIFICANCE OF HUMAN T-LYMPHOTROPIC VIRUS TYPE-I INDETERMINANT SEROLOGICAL FINDINGS AMONG HEALTHY-INDIVIDUALS VOX SANGUINIS LIPKA, J. J., Young, K. K., Kwok, S. Y., Reyes, G. R., Sninsky, J. J., Foung, S. K. 1991; 61 (3): 171-176

Abstract

Follow-up studies on 67 blood donors with indeterminant serological findings for human T-lymphotropic virus (HTLV) type I by standard immunoassays showed no evidence of infection by polymerase chain reaction analysis for HTLV-I or HTLV-II nucleic acids or by antibody reactivity to a unique HTLV-I recombinant envelope protein, MTA-4. Among HTLV-I- or -II-infected individuals, a history of blood transfusion, past residence in established HTLV-I endemic areas or some association with intravenous drug use were common. In contrast, 85% of indeterminant cases had none of these risk factors. These observations suggest that healthy individuals with indeterminant serology for HTLV-I should not require additional studies.

View details for Web of Science ID A1991GR19300003

View details for PubMedID 1725466