Intense focus has been centered around how the primary cilia transduces the hedgehog (Hh) signal from smoothened (Smo) to the Gli transcription factors. New data indicate that ligand and signaling lipids help regulate small GTPase-dependent accumulation and activity of signaling components.
View details for DOI 10.1016/j.ceb.2007.10.008
View details for Web of Science ID 000252143000014
View details for PubMedID 18061425