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Mid-infrared reflectivity of experimental atheromas JOURNAL OF BIOMEDICAL OPTICS Holman, H. N., Bjornstad, K. A., Martin, M. C., McKinney, W. R., Blakely, E. A., Blankenberg, F. G. 2008; 13 (3)

Abstract

We report that the pathologic components present within the atheromatous plaques of ApoE knock-out mice can reflect significant amounts of mid-infrared (mid-IR) light. Furthermore, the reflected light spectra contained the unique signatures of a variety of biologic features including those found in unstable or "vulnerable" plaque. This discovery may represent a unique opportunity to develop a new intravascular diagnostic modality that can detect and characterize sites of atherosclerosis.

View details for DOI 10.1117/1.2937469

View details for Web of Science ID 000257951200003

View details for PubMedID 18601520