Inhibition and attention in adolescents with nonmanic mood disorders and a high risk for developing mania JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY Singh, M. K., DelBello, M. P., Fleck, D. E., Shear, P. K., Strakowski, S. M. 2009; 31 (1): 1-7


This study examines psychomotor inhibition, sustained attention, and inhibitory attentional control in adolescents (ages 12-18 years) with a nonmanic mood disorder and with a first-degree relative with bipolar I disorder (MD, N = 20) and demographically matched healthy children of parents without any psychiatric disorder (HC, N = 13). MD participants showed abnormal performance in stop signal reaction time and latency (d = 1.28 and 1.64, respectively), sustained attention response bias (d = 0.75), and color naming speed (d = 0.88). The results indicate that MD participants exhibit psychomotor disinhibition, marginal cognitive slowing and cautious response biases, but no formal deficits in sustained or selective attention.

View details for DOI 10.1080/13803390801945038

View details for Web of Science ID 000261739200001

View details for PubMedID 18608697