Multilevel Modeling in Psychosomatic Medicine Research PSYCHOSOMATIC MEDICINE Myers, N. D., Brincks, A. M., Ames, A. J., Prado, G. J., Penedo, F. J., Benedict, C. 2012; 74 (9): 925–36


The primary purpose of this study is to provide an overview of multilevel modeling for Psychosomatic Medicine readers and contributors. The article begins with a general introduction to multilevel modeling. Multilevel regression modeling at two levels is emphasized because of its prevalence in psychosomatic medicine research. Simulated data sets based on some core ideas from the Familias Unidas effectiveness study are used to illustrate key concepts including communication of model specification, parameter interpretation, sample size and power, and missing data. Input and key output files from Mplus and SAS are provided. A cluster randomized trial with repeated measures (i.e., three-level regression model) is then briefly presented with simulated data based on some core ideas from a cognitive-behavioral stress management intervention in prostate cancer.

View details for DOI 10.1097/PSY.0b013e3182736971

View details for Web of Science ID 000311131800009

View details for PubMedID 23107843

View details for PubMedCentralID PMC3498540