Effectiveness and cost of organized outreach for colorectal cancer screening: A Randomized Controlled Trial. Journal of the National Cancer Institute Somsouk, M. n., Rachocki, C. n., Mannalithara, A. n., Garcia, D. n., Laleau, V. n., Grimes, B. n., Issaka, R. B., Chen, E. n., Vittinghoff, E. n., Shapiro, J. A., Ladabaum, U. n. 2019


Colorectal cancer (CRC) screening remains underutilized especially in safety-net systems. The objective of this study was to determine the effectiveness, costs, and cost-effectiveness of organized outreach using fecal immunochemical tests (FIT) compared with usual care.Patients aged 50-75 years eligible for CRC screening from eight participating primary care safety-net clinics were randomized to outreach intervention with usual care versus usual care alone. The intervention included a mailed postcard and call, followed by a mailed FIT kit, and a reminder phone call if the FIT kit was not returned. The primary outcome was screening participation at one year and a microcosting analysis of the outreach activities with embedded long-term cost-effectiveness of outreach. All statistical tests were two-sided.5,386 patients were randomized to the intervention group and 5,434 to usual care. FIT screening was statistically significantly higher in the intervention group than in the control group (57.9% vs. 37.4%, P?

View details for DOI 10.1093/jnci/djz110

View details for PubMedID 31187126