Cryosurgical ablation for treatment of rhinitis: A prospective multicenter study. The Laryngoscope Chang, M. T., Song, S. n., Hwang, P. H. 2019


To assess the efficacy and safety of cryoablation of the posterior nasal nerve (PNN) for treatment of chronic rhinitis.This was a prospective single-arm trial of 98 adult patients at six U.S. centers with chronic allergic and nonallergic rhinitis. PNN cryoablation was performed in-office under local anesthesia using a handheld device. Patients discontinued use of intranasal ipratropium 3?days prior to treatment and throughout the study period. Reflective Total Nasal Symptom Score (rTNSS) was measured at pretreatment baseline and posttreatment at 1 month, 3 months, 6 months, and 9 months. The Rhinoconjunctivitis Quality of Life Questionnaire (RQLQ) was completed at pretreatment and 3 months posttreatment. Adverse effects and postprocedure medication usage were recorded.Ninety-eight procedures (100%) were successfully completed. rTNSS significantly improved over pretreatment baseline (6.1?±?1.9) at 1 month (2.9?±?1.9, P?

View details for DOI 10.1002/lary.28301

View details for PubMedID 31566744