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Molecular Basis and Clinical Implications of Opioid Tolerance and Opioid- Induced Hyperalgesia Acute Pain Management Chu, L. F., Clark, J., Angst, M. S. edited by Sinatra, R. S., deLeon-Casasola, O. A., Ginsberg, B., Viscusi, E. R. Cambridge University Press. 2009: 114–143