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Comparing enhanced versus standard Diabetes Prevention Program among indigenous adults in an urban setting: a randomized controlled trial. BMC public health Rosas, L. G., Vasquez, J. J., Hedlin, H. K., Qin, F. F., Lv, N. n., Xiao, L. n., Kendrick, A. n., Atencio, D. n., Stafford, R. S. 2020; 20 (1): 139


Indigenous people in the United States are at high risk for diabetes. Psychosocial stressors like historical trauma may impede success in diabetes prevention programs.A comparative effectiveness trial compared a culturally tailored diabetes prevention program (standard group) with an enhanced one that addressed psychosocial stressors (enhanced group) in 2015 to 2017. Participants were 207 Indigenous adults with a body mass index (BMI) of =30 and one additional criterion of metabolic syndrome, and were randomized to the standard or enhanced group. Both groups received a culturally tailored behavioral diabetes prevention program. Strategies to address psychosocial stressors were provided to the enhanced group only. Change in BMI over 12?months was the primary outcome. Secondary outcomes included change in quality of life, and clinical, behavioral, and psychosocial measures at 6 and 12?months.The two groups did not significantly differ in BMI change at 12?months. The two groups also did not differ in any secondary outcomes at 6 or 12?months, with the exception of unhealthy food consumption; the standard group reported a larger mean decrease (95% CI) in consumption of unhealthy food compared with the enhanced group (-?4.6 [-?6.8, -?2.5] vs. -0.7 [-?2.9, 1.4], p?=?0.01). At 6?months, significant improvements in weight and the physical component of the quality of life measure were observed for both groups compared with their baseline level. Compared with baseline, at 12?months, the standard group showed significant improvement in BMI (mean [95% CI], -?0.5 [-?1.0, -?0.1]) and the enhanced group showed significant improvement in the physical component of the quality of life (2.9 [0.7, 5.2]).Adding strategies to address psychosocial barriers to a culturally tailored diabetes prevention program was not successful for improving weight loss among urban Indigenous adults.(if applicable): NCT02266576. Registered October 17, 2014 on The trial was prospectively registered.

View details for DOI 10.1186/s12889-020-8250-7

View details for PubMedID 32000738