Uterine leiomyosarcoma manifesting as a tricuspid valve mass. Case reports in oncology Marak, C. P., Ponea, A. M., Alappan, N., Shaheen, S., Guddati, A. K. 2013; 6 (1): 119-26

Abstract

Uterine leiomyosarcoma is a rare malignancy and carries a poorer prognosis when compared to endometrial carcinoma. It has been observed to metastasize to all the major organs. It presents with symptoms of abdominal distension, vaginal bleeding and may pass unnoticed until an advanced stage in patients with leiomyomas. Surgery is a viable option in patients with disease limited to the uterus, but metastasis to the heart may require surgery to prevent acute and catastrophic complications. The case described here involves metastasis to the tricuspid valve, which caused severe tricuspid regurgitation in the setting of acute pulmonary embolism. Surgical resection restored cardiac function and stabilized the patient. This case illustrates a rare site of metastasis of leiomyosarcoma which required immediate intervention and resulted in a favorable outcome.

View details for DOI 10.1159/000346935

View details for PubMedID 23569446

View details for PubMedCentralID PMC3618104