Minimally Invasive Versus Open Liver Resection for Hepatocellular Carcinoma in the Setting of Portal Vein Hypertension: Results of an International Multi-institutional Analysis. Annals of surgical oncology Ruzzenente, A. n., Bagante, F. n., Ratti, F. n., Alaimo, L. n., Marques, H. P., Silva, S. n., Soubrane, O. n., Endo, I. n., Sahara, K. n., Beal, E. W., Lam, V. n., Poultsides, G. A., Makris, E. A., Popescu, I. n., Alexandrescu, S. n., Martel, G. n., Workneh, A. n., Hugh, T. J., Guglielmi, A. n., Aldrighetti, L. n., Pawlik, T. M. 2020


Patients with hepatocellular carcinoma (HCC) and portal vein hypertension assessed with platelet count (PVH-PLT; platelet count? ?7 days; non-MIS: 55% vs. MIS: 29%), as well as higher morbidity (non-MIS: 42% vs. MIS: 29%) [p?<0.001]. In contrast, long-term oncological outcomes were comparable, including 3-year overall survival (non-MIS: 66.2% vs. MIS: 72.9%) and disease-free survival (non-MIS: 47.3% vs. MIS: 50.2%) [both p?=?0.08].An MIS approach was associated with improved short-term outcomes, but similar long-term outcomes, compared with open liver resection for patients with HCC and PVH-PLT. An MIS approach for liver resection should be considered for patients with HCC, even those individuals with PVH-PLT.

View details for DOI 10.1245/s10434-020-08444-3

View details for PubMedID 32274662