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National postoperative and oncologic outcomes after pelvic exenteration for T4b rectal cancer. Journal of surgical oncology Konstantinidis, I. T., Lee, B. n., Trisal, V. n., Paz, I. n., Melstrom, K. n., Sentovich, S. n., Lai, L. n., Raoof, M. n. 2020

Abstract

Studies reporting outcomes after pelvic exenteration for rectal cancer are limited. The objective of this study was to evaluate early postoperative and oncologic outcomes in a national multi-institutional cohort.Using the National Cancer Database (NCDB), which collects data from over 1500 commission on cancer (CoC)-accredited hospitals, we analyzed patients undergoing pelvic exenteration for T4b rectal adenocarcinoma.There were 1367 pelvic exenterations performed in 552 hospitals. Median age was 60 years, the majority of patients (n?=?831; 60.8%) were female. Neoadjuvant radiation was used only in 57%; 24.3% of resections had positive margins. Following exenteration, 30-day mortality rate, 90-day mortality rate, and readmission rates were: 1.8%, 4.4%, and 7.4%. Age?=?60 years and higher Charlson-Deyo comorbidity index were independently associated with increased 90-day mortality (P?

View details for DOI 10.1002/jso.26058

View details for PubMedID 32516469