Delayed blood transfusion is associated with mortality following radical cystectomy. Scandinavian journal of urology Tan, W. S., Wang, Y. n., Trinh, Q. D., Preston, M. A., Kelly, J. D., Hrouda, D. n., Kibel, A. S., Krasnow, R. E., Liu, J. J., Chung, B. I., Chang, S. L., Mossanen, M. n. 2020: 1–7


Objectives: To examine the temporal association between blood transfusion and 90-day mortality in patients with bladder cancer treated with radical cystectomy.Methods: This represents a retrospective cohort study of patients treated with radical cystectomy within the Premier Hospital network between 2003 and 2015. Patients outcomes were stratified those who received early blood transfusion (day of surgery) vs delayed blood transfusion (postoperative day =1) during the index admission. Primary end point was 90-day mortality following surgery.Results: The median age of 12,056 patients identified was 70 years. A total of 7,201 (59.7%) patients received blood transfusion. Within 90?days following surgery, 57 (2.2%), 162 (5.9%) and 123 (6.7%) patients in the early, delayed and both early and delayed transfused patients died respectively. Following multivariate logistic regression to account for patient (age and Charlson Comorbidity Index [CCI]) and hospital (surgeon volume, surgical approach and academic status) factors, delayed blood transfusion was independently associated with 90-day mortality (Odds ratio [OR], 2.64; 95% Confidence Interval [CI], 1.98-3.53; p?

View details for DOI 10.1080/21681805.2020.1777195

View details for PubMedID 32538224