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The Role of Dopamine in Reward-Related Behavior: Shining New Light on an Old Debate. Journal of neurophysiology Wang, A. R., Groome, A. M., Taniguchi, L. n., Eshel, N. n., Bentzley, B. S. 2020

Abstract

The role dopamine plays in reward-related behaviors has been debated for decades. Heymann et al. (Heymann G, Jo YS, Reichard KL, McFarland N, Chavkin C, Palmiter RD, Soden ME, Zweifel LS. Neuron 105(5): 909-920, 2020) identify subpopulations of dopamine-producing neurons that separately mediate reward association and motivation. Their results help demonstrate that dopamine signaling may partake in both reinforcement learning and incentive salience functions, instantiated by neuropeptide-defined subpopulations of the VTA with different projection targets.

View details for DOI 10.1152/jn.00323.2020

View details for PubMedID 32639896