The association between circulating total testosterone (T) levels and clinically significant PCa is still a matter of debate. In this study, we evaluated whether serum testosterone levels may have a role in predicting unfavorable disease (UD) and biochemical recurrence (BCR) in patients with clinically localized (=?cT2c) ISUP grade group 1 PCa at biopsy.408 patients with ISUP grade group 1 prostate cancer, undergone to radical prostatectomy and T measurement were included. The outcome of interest was the presence of unfavourable disease (UD) defined as ISUP grade group [Formula: see text] 3 and/or pT [Formula: see text] 3a.Statistically significant differences resulted between serum testosterone values and ISUP grade groups (P?
View details for DOI 10.1007/s00345-020-03368-9
View details for PubMedID 32683462