Serum high-density lipoprotein cholesterol serves as a prognostic marker for light-chain cardiac amyloidosis. International journal of cardiology Yang, T. n., Wan, K. n., Song, R. n., Guo, X. n., Xu, Y. n., Wang, J. n., Zhang, Q. n., Alexander, K. M., Liao, R. n., Chen, Y. n. 2020

Abstract

Oxidative stress and inflammation are central in the pathophysiology of light-chain amyloid cardiomyopathy (AL-CM). High-density lipoprotein cholesterol (HDLC) is an antioxidant and acts as an anti-inflammatory regulator. In this study, the prognostic value of serum HDL-C was explored in AL-CM.In this prospective single-center study, two hundred consecutive patients with biopsy-confirmed light-chain amyloidosis (AL) and cardiac involvement were enrolled. Patients were classified into low or normal serum HDL-C groups (HDL-C?

View details for DOI 10.1016/j.ijcard.2020.10.034

View details for PubMedID 33080283