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Nationwide Cost-Effectiveness Analysis of Surgical Stabilization of Rib Fractures by Flail Chest Status and Age Groups. The journal of trauma and acute care surgery Choi, J., Mulaney, B., Laohavinij, W., Trimble, R., Tennakoon, L., Spain, D. A., Salomon, J. A., Goldhaber-Fiebert, J. D., Forrester, J. D. 2020

Abstract

SSRF is increasingly utilized to manage patients with rib fractures. Benefits of performing SSRF appear variable and the procedure is costly, necessitating cost-effectiveness analysis for distinct subgroups. We aimed to assess the cost-effectiveness of surgical stabilization of rib fractures (SSRF) vs non-operative management among patients with rib fractures aged <65 vs =65 years, with vs without flail chest. We hypothesized that compared to non-operative management, SSRF is cost-effective only for patients with flail chest.This economic evaluation used a decision-analytic Markov model with a lifetime time horizon incorporating US population-representative inputs to simulate benefits and risks of SSRF compared to non-operative management. We report quality-adjusted life-years (QALYs), costs, and incremental cost-effectiveness ratios (ICERs). Deterministic and probabilistic sensitivity analyses accounted for most plausible clinical scenarios.Compared to non-operative management, SSRF was cost-effective for patients with flail chest at willingness-to-pay threshold of $150,000/QALY gained. SSRF cost $25,338 and $123,377/QALY gained for those with flail chest aged <65 and =65 years, respectively. SSRF was not cost-effective for patients without flail chest; costing $172,704 and $243,758/QALY gained for those aged <65 and =65 years, respectively. One-way sensitivity analyses showed that under most plausible scenarios, SSRF remained cost-effective for subgroups with flail chest and non-operative management remained cost-effective for patients aged >65 without flail chest. Probability that SSRF is cost-effective ranged from 98% among patients aged <65 with flail chest to 35% among patients aged =65 without flail chest.SSRF is cost effective for patients with flail chest. SSRF may be cost-effective in some patients without flail chest, but delineating these patients requires further study.level II.

View details for DOI 10.1097/TA.0000000000003021

View details for PubMedID 33559982