Interferon-gamma release assay testing to assess COVID-19 vaccination response in a SARS-CoV-2 seronegative patient on rituximab: a case report. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases Ferguson, J., Murugesan, K., Banaei, N., Liu, A. 2021


We describe the case of a 44-year-old female on Rituximab for treatment of multiple sclerosis with undetectable SARS-CoV-2 IgG specific antibodies eighteen days after second dose of SARS-CoV-2 vaccine. Interferon-gamma release assay testing for SARS-CoV-2 was positive on day nineteen, demonstrating robust T-cell mediated response despite lack of antibody-mediated response.

View details for DOI 10.1016/j.ijid.2021.06.054

View details for PubMedID 34216738