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Dysgeusia and Dysosmia in Chronic Kidney Disease: NHANES 2011-2014. Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation Vengalasetti, Y. V., Chertow, G. M., Popat, R. 2021

Abstract

OBJECTIVE: Dysgeusia and dysosmia are known to be associated with end-stage renal disease. Whether dysgeusia and dysosmia are associated with nondialysis-requiring chronic kidney disease (CKD) is unknown.METHODS: We utilized data from the National Health and Nutrition Examination Survey during years 2011-14. We classified CKD by stage using standard criteria for the estimated glomerular filtration rate and the urine albumin-to-creatinine ratio. We used multivariable logistic regression analysis to determine the independent associations among CKD, CKD stage, and dysgeusia and dysosmia using a ChemoSensory Questionnaire.RESULTS: After adjusting for the residual effects of age, sex, self-reported race, and diabetes, nondialysis-requiring CKD was significantly associated with dysgeusia ([odds ratio, 95% confidence interval] 1.34 [1.05, 1.70]); the association with dysosmia was of borderline significance, odds ratio 1.27 (0.97, 1.68). Odds of dysgeusia were higher at more severe CKD stages.CONCLUSION: Nondialysis-requiring CKD is significantly associated with self-reported dysgeusia.

View details for DOI 10.1053/j.jrn.2021.11.003

View details for PubMedID 35339348