Notice: Users may be experiencing issues with displaying some pages on stanfordhealthcare.org. We are working closely with our technical teams to resolve the issue as quickly as possible. Thank you for your patience.
 

See our updated masking policy »

Stanford Health Care

Critical Care Cardiology Trials Network (CCCTN): a cohort profile. European heart journal. Quality of care & clinical outcomes Metkus, T. S., Baird-Zars, V. M., Alfonso, C. E., Alviar, C. L., Barnett, C. F., Barsness, G. W., Berg, D. D., Bertic, M., Bohula, E. A., Burke, J., Burstein, B., Chaudhry, S. P., Cooper, H. A., Daniels, L. B., Fordyce, C. B., Ghafghazi, S., Goldfarb, M., Katz, J. N., Keeley, E. C., Keller, N. M., Kenigsberg, B., Kontos, M. C., Kwon, Y., Lawler, P. R., Leibner, E., Liu, S., Menon, V., Miller, P. E., Newby, L. K., O'Brien, C. G., Papolos, A. I., Pierce, M. J., Prasad, R., Pisani, B., Potter, B. J., Roswell, R. O., Sinha, S. S., Shah, K. S., Smith, T. D., Snell, R. J., So, D., Solomon, M. A., Ternus, B. W., Teuteberg, J. J., van Diepen, S., Zakaria, S., Morrow, D. A. 2022

Abstract

The aims of the Critical Care Cardiology Trials Network (CCCTN) are to develop a registry to investigate the epidemiology of cardiac critical illness and to establish a multicenter research network to conduct randomized clinical trials (RCTs) in patients with cardiac critical illness.The CCCTN was founded in 2017 with 16 centers and has grown to a research network of over 40 academic and clinical centers in the United States and Canada. Each center enters data for consecutive cardiac intensive care unit (CICU) admissions for at least two months of each calendar year. More than 20 000 unique CICU admissions are now included in the CCCTN Registry. To date, scientific observations from the CCCTN Registry include description of variations in care, the epidemiology and outcomes of all CICU patients, as well as subsets of patients with specific disease states, such as shock, heart failure, renal dysfunction, and respiratory failure. The CCCTN has also characterized utilization patterns, including use of mechanical circulatory support in response to changes in the heart transplantation allocation system, and the use and impact of multidisciplinary shock teams. Over years of multicenter collaboration, the CCCTN has established a robust research network to facilitate multicenter registry-based randomized trials in patients with cardiac critical illness.The CCCTN is a large, prospective registry dedicated to describing processes-of-care and expanding clinical knowledge in cardiac critical illness. The CCCTN will serve as an investigational platform from which to conduct randomized controlled trials in this important patient population.

View details for DOI 10.1093/ehjqcco/qcac055

View details for PubMedID 36029517