The Evolution of Fluorescence-Guided Surgery. Molecular imaging and biology Van Keulen, S., Hom, M., White, H., Rosenthal, E. L., Baik, F. M. 2022


There has been continual development of fluorescent agents, imaging systems, and their applications over the past several decades. With the recent FDA approvals of 5-aminolevulinic acid, hexaminolevulinate, and pafolacianine, much of the potential that fluorescence offers for image-guided oncologic surgery is now being actualized. In this article, we review the evolution of fluorescence-guided surgery, highlight the milestones which have contributed to successful clinical translation, and examine the future of targeted fluorescence imaging.

View details for DOI 10.1007/s11307-022-01772-8

View details for PubMedID 36123445